Compare and Contrast the Developments That Led to One Market Drug Launched in the Mid-20th Century and One...

Compare and contrast the developings that led to one merchandise do drugs launched in the mid-20th century and one launched in the past 25 years. Over a long period of beat, the cost and the period taken for drug ontogeny has soared. The two examples that have been selected to class and contrast are penicillin and sildenafil citrate; where both have been arrived serendipitously. Penicillin show changed the course of medicine as the active ingredient that was obtain turned out to be an infection-fighting agent of enormous potency. The suppuration of penicillin has served as the general model for most drug outgrowth and find during this specific time period. Research that resulted in sildenafil was originally conducted in order to find a trio compound with anti-hypertensive properties and over time a turning nous had occurred, perhaps not the final one, where a completely brisk indication has been developed. In the early 20th century, a pandemic of diseases arose as a result of bacterial infections which killed many individuals delinquent to the lack of available antibiotics. It was this series of incurable diseases that spurred research into drugs that could gravel across conditions caused by bacterial infection. In 1928, a stinting life scientist named Alexander Fleming made a serendipitous discovery of the antibiotic penicillin.

On observation of the Staphylococci culture plates leftfield for several(prenominal) weeks, he noticed contamination by fungi (Brown, 2005). round the fungi  hurls were zones of inhibition, suggestive of  an agent or substance containing anti-bacterial pro perties beingness produced it. During furth! er analysis, he realised that only the Penicillium  mildew produces this substance. The substance was then consequently named Penicillin and became available on the commercialize in 1942 (Brown, 2005).  [pic] Figure 1. Chemical structure of Penicillin (Fukami, T et al., 2006). Penicillin is a class of drug called beta-lactam antibiotics (Joint Formulary Committee, 2012). A...If you want to get a full essay, order it on our website: BestEssayCheap.com

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